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The Molecular Basis of Cancer 4th Edition by John Mendelsohn, et al {PDF} [BE]

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 							The Molecular Basis of Cancer 4th Edition by John Mendelsohn, et al. {PDF} [BE]
  
  
  
  The Molecular Basis of Cancer 4th edition by John Mendelsohn MD, Peter M. Howley MD, Mark A.
Israel MD, Joe W. Gray PhD, Craig B. Thompson MD
  
  
  
  The Molecular Basis of
Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly
revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant
transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the
molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in
clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new
approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday
clinical application.
  
  Effectively determine the course of malignancy and design appropriate treatment
protocols by understanding the scientific underpinnings of cancer.
  
  Visually grasp and retain difficult
concepts easily thanks to a user-friendly format with abundant full-color figures.
  
  Find critical
information quickly with chapters following a logical sequence that moves from pathogenesis to therapy.
  
 
Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight
brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers
Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic
Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology.
  
  Access the entire
text and illustrations online, fully searchable, at Expert Consult.
  
  File
Details
  
  Genre: Non-Fiction, Medical
  Publisher: Saunders; 4 edition (March 5, 2014)
  Language: English
  ISBN-10: 1455740667
  ISBN-13: 978-1455740666
  
  Book Contents
  
  Part I: Carcinogenesis and Cancer Genetics
 

  1. Cancer, A Genetic Disorder
  
  2. Oncogenes and Signal Transduction
  
  3. Tumor
Suppressor Genes
  
  4. Genomic Instability and DNA Repair
  
  5. Epigenetics and Cancer
 

  6. Infectious Agents and Cancer
  
  7. Environmental Carcinogenesis
  
  8. Animal Models:
Flies, Fish and Yeast
  
  9. Genetic Mouse Models of Cancer
  
  Part II: Cancer Biology
  
  10. Cancer Stem Cells
  
  11. Regulation of the Cell Cycle
  
  12. Cell Growth
 

  13. Cancer Cell Metabolism
  
  14. Apoptosis, Autophagy and Necrosis
  
  15. Cell Growth
Arrest and Senescence
  
   16. Stromal-Cancer Interactions in the Microenvironment
  
   17.
Hypoxia and Angiogenesis
  
  18. Invasion and Metastasis
  
  19. Inflammation and Cancer
 

   20. Molecular Pathways and Systems Biology
  
  Part III: Molecular Pathology and
Diagnostics
  
  21. Biomarkers Assessing Risk of Cancer
  
  22. Biomarkers for Detecting
Cancer: Molecular Screening
  
   23. Biomarkers for Predicting Response to Specific Therapy
  
 
24. The Technology of Analyzing Nucleic Acids
  
  25. Imaging Cancer
  
   
  
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